Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep1055 | Hot topics (including COVID-19) | ECE2020

The effects of selective activation of kisspeptin neurons in hypothalamic arcuate nucleus on energy metabolism in mice

Li Qian , Liu Qinyu , Huang Guifeng , Lin Wei , Chen Gang , Wen Junping

Objectives: This study aims to determine which metabolic tissue is involved in the process of kisspeptin neurons regulate energy metabolism so that it may provide a novel therapy for metabolic related diseases such as obesity.Methods: Kiss1-CreGFP mice were used in this study. And we selectively activated kisspeptin neurons by using Designer-receptors-exclusively-activated-by-designer-drugs (DREADDs) technology. Mice were bilaterally injected with the Cr...